Select Publications

Basundra R, Kapoor S, Hollville E, Kiapour N, Lopez AB, Melchiorre NM, Deshmukh M. 2022. Constitutive High Expression of NOXA Sensitizes Human Embryonic Stem Cells for Rapid Cell Death.  Stem Cells.

Swahari V, Nakamura A, Hollville E, Stroud H, Simon J, Ptacek T, Beck M, Flowers C, Guo J, Plestant C, Liang J, Kurtz L, Kanke M, Hammons S, He YW, Anton ES, Sethupathy P, Moy S, Greenberg M, Deshmukh M. 2021. MicroRNA-29 is an essential regulator of brain maturation through regulation of CH methylation. Cell Reports. 35(1): 108946

Geden MJ, Romero SE, Deshmukh M. 2021. p53 is required for nuclear but not mitochondrial DNA damage-induced degeneration. Cell Death Dis. 12(1):104

Hollville, E., Joers, V., Nakamura, A, Swahari, V., Tansey, M., Moy, S., Deshmukh, M. 2020.  Characterization of a Cul9–Parkin double knockout mouse model for Parkinson’s disease. Scientific Reports. 10:16886

Hollville, E., Romero, SE., Deshmukh, M. 2019. Apoptotic cell death regulation in neurons. The FEBS Journal. 286(17)

Geden, MJ., Romero, SE., Deshmukh, M. 2019. Apoptosis versus axon pruning: Molecular intersection of two distinct pathways for axon degeneration. Neurosci Res. 139:3-8

Hollville, E., Deshmukh, M. 2018. Physiological functions of non-apoptotic caspase activity in the nervous system. Sem Cell Dev Biol. 11.037

Geden, MJ., Deshmukh, M. 2016. Axon degeneration: context defines distinct pathways. Curr Opin Neurobiol.39:108–115

Nakamura, A., Swahari, V., Plestant, ., Smith, I., McCoy, E., Smith, S., Moy, SS., Anton, ES., and M. Deshmukh. 2016. Bcl-xL Is Essential for the Survival and Function of Differentiated Neurons in the Cortex That Control Complex Behaviors. J. Neurosci. 36(20):5448 –5461

Swahari, V., Nakamura, A., Baran-Gale, J., Garcia, I., Crowther, AJ., Sons, R., Gershon, TR., Hammond, S., Sethupathy, P., M Deshmukh. 2016. Essential Function of Dicer in Resolving DNA Damage in the Rapidly Dividing Cells of the Developing and Malignant Cerebellum. Cell Reports. 10.1016

Cliffe AR, Arbuckle JH, Vogel JL, Geden MJ, Rothbart SB, Cusack CL, Strahl BD, Kristie TM, Deshmukh M. 2015. Neuronal Stress Pathway Mediating a Histone Methyl/Phospho Switch Is Required for Herpes Simplex Virus Reactivation. Cell Host Microbe. 18(6):649-58.

Gama, V., Deshmukh M. 2015. Life after MOMP. Mol Cell. 58(2):199-201.Gama, V., Swahari, V., Schafer, J., Kale, A.J., Evans, A., Huang, Y., Cliffe, A., Golitz, B., Sciaky, N., Pei, X.H., Xiong, Y., and M. Deshmukh. 2014. The E3 ligase PARC mediates the degradation of cytosolic cytochrome c to promote survival in neurons and cancer cells. Sci. Signal. 7(334).

Cusack, C.L., V. Swahari, W.H. Henley, J.M. Ramsey, and M. Deshmukh. 2013. Distinct Pathways Mediate Axon Degeneration during Apoptosis and Axon-Specific Pruning. Nat. Commun. 4: 1876.

Kole, AJ., Annis, RP., and Deshmukh, M. 2013. Mature Neurons: Equipped for Survival. Cell Death & Dis. 4:e689.

Dumitru, R*., V. Gama*, M. Fagan, J.J. Bower, V. Swahari, L.H. Pevny, M. Deshmukh. 2012. Human Embryonic Stem Cells have Constitutively Active Bax at the Golgi and are Primed to Undergo Rapid Apoptosis. Mol Cell. 46:573-583. (Featured Preview Article) *Equal Contribution

Kole, A.J., V. Swahari, S.M. Hammond, and M. Deshmukh. 2011. miR-29b is Activated During Neuronal Maturation and Targets BH3-only Genes to Restrict Apoptosis. Genes & Dev. 25:125-130.

Vaughn, A.E and M. Deshmukh. 2008. Glucose Metabolism Inhibits Apoptosis in neurons and Cancer Cells by Redox Inactivation of Cytochrome c. Nat. Cell Biol.. 10:1477-1483.

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